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About Flutiform Transhaler (Fluticasone - Formoterol)

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Also known as:  Fluticasone - Formoterol.


Flutiform Transhaler is used for the management of asthma and COPD, with chronic bronchitis and emphysema inclusively, in people who need the regular treatment and in whom the use of a combination inhaler is appropriate. Flutiform Transhaler contains two active ingredients called Fluticasone and Formoterol. Fluticasone belongs to a group of medicines known as corticosteroids, which help reduce swelling and inflammation in the lungs by blocking the release of allergy-triggering substances. Formoterol is a long-acting beta2-adrenergic agonist that relaxes muscles surrounding the airways of the lungs, widening the air passes for easier breathing. The medication reduces the inflammation in the lungs and alleviates symptoms like wheezing, cough, shortness of breath, and chest tightness, but it is not effective if a patient is already having an asthma attack. In this case, a fast-acting 'reliever' is required.


Maintenance treatment of asthma where the use of a combination drug (an inhaled corticosteroid and a long-acting beta2-agonist) is appropriate.

Symptomatic treatment of COPD, including chronic bronchitis and emphysema.

MOA (mechanism of action)

Fluticasone is a synthetic trifluorinated glucocorticoid with potent and sustained anti-inflammatory effects. When inhaled, it is absorbed into the cells of the airways and works by preventing the release of mediators like histamines, eicosanoids, cytokines, and leukotrienes, involved in the inflammation of the lungs. Fluticasone is also involved in the preclusion of excess mucus formation that blocks the airflow into the lungs, allowing the airways to widen and facilitating breathing.

Formoterol is a long-acting selective beta2-adrenergic receptor agonist which acts locally in the lungs and provides rapid bronchodilation, with the onset of action within 1-3 minutes and the duration of effect up to 12 hours after a single dose intake. Formoterol operates by stimulating beta-2 adrenergic receptors, causing the smooth muscle relaxation that opens up the airways and makes it easier to breathe.


For asthma treatment:

  • Adults (18 years of age and older) - 2 inhalations (puffs) in the morning and 2 inhalations (puffs) in the evening; maximum dose - 1000 mcg a day.
  • Adolescents (12 - 18 years of age) - 2 inhalations (puffs) in the morning and 2 inhalations (puffs) in the evening; maximum dose - 500 mcg a day.

For COPD treatment:

  • Adults (18 years of age and older) - 2 inhalations (puffs) in the morning and 2 inhalations (puffs) in the evening; maximum dose - 1000 mcg a day.

Flutiform Transhaler should be used on a long-term and daily basis for the maintenance treatment of asthma, even when patients are asymptomatic. They should be assessed regularly by their doctor to maintain the optimum dosage. If one has difficulties with synchronizing aerosol actuator and inspiration of breath, the use of an appropriate spacing device may be needed to help take the medicine correctly.

How to use Flutiform Transhaler:

  • Remove the mouthpiece cover and shake the inhaler.
  • Breathe out slowly and as deeply as possible.
  • Hold your inhaler upright and put the mouthpiece in your mouth with your lips around it (do not bite the mouthpiece).
  • Breathe in slowly and deeply through your mouth and, at the same time, press down on the canister to release one puff.
  • Hold your breath for 10 seconds or as long as is comfortable.
  • Remove the inhaler from your mouth and breathe out slowly.
  • Keep the inhaler in a vertical position for about half a minute and then shake the inhaler prior to repeating steps 2 to 5.
  • Replace the mouthpiece cover.
  • Rinse your mouth out or brush your teeth after you have used your inhaler.

How to clean Flutiform Transhaler:

  • Remove the mouthpiece cover.
  • Do not remove the canister from the actuator as this can interfere with the dose counter.
  • Wipe the inside and outside of the mouthpiece and the outside of the actuator with a clean, dry cloth or tissue.
  • Replace the mouthpiece cover.
  • Do not put the metal canister into the water.
  • Clean your inhaler at least once a week.

How to use Flutiform Transhaler with a ‘spacer’ device:

  • Hold the inhaler upright and place your thumb on the bottom and index finger on the top.
  • Carefully shake the inhaler several times up and down.
  • Insert the mouthpiece into the backpiece of the chamber.
  • Put the spacer’s mouthpiece into your mouth and hold it firmly between your lips (do not bite it).
  • Press down on the aerosol canister one time with your index finger. This will release one puff into the spacer.
  • Take a few deep and slow breaths to inhale the medicine into your lungs.
  • Take the spacer out of your mouth and hold your breath for at least 10 seconds.
  • Rinse your mouth thoroughly with water or brush your teeth.
Missed dose

If you miss a dose of Flutiform Transhaler you should take it as soon as you remember. If it is the time for the next dose you should continue your regular dosing schedule. Do not exceed the doctor’s recommended dose.


If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.


Store at room temperature between 15°C and 30°C (59°F and 86°F) and away from excess moisture and heat. The medication should not be refrigerated. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Flutiform Transhaler are:

  • headache
  • fever
  • nausea
  • vomiting
  • upper respiratory tract infection
  • sore throat
  • cough
  • dry mouth
  • hoarseness of voice
  • fungal infections in the mouth
  • runny nose
  • sneezing
  • dizziness
  • weakness
  • upset stomach
  • diarrhea
  • insomnia
  • musculoskeletal (bone, muscle or joint) pain
  • palpitations

Side effects occurrence does not only depend on the medication you are taking but also on your overall health and other factors.


Do not take Flutiform Transhaler if you are allergic to Fluticasone, Formoterol or any other ingredients present in the formulation.

Do not use the formulation is you have serious cardiovascular disorders, cardiac rhythm abnormalities, hypokalemia.

Do not take the medication if you have pulmonary tuberculosis.

Do not use Flutiform Transhaler if you suffer from thyrotoxicosis (excessive production of thyroid hormone by the thyroid gland).

Do not take the drug if you have severe liver problems.

Do not use the preparation if you have diabetes mellitus (as this may increase blood sugar levels).

Do not use the drug concomitantly with medicines known as beta-blockers (like atenolol, sotalol, metoprolol, timolol), other medications used to treat asthma or breathing conditions (e.g., aminophylline or theophylline), antihistamine medications, diuretics, drugs to treat heart failure (such as digoxin), medicines to treat abnormal heart rhythms (like quinidine, procainamide, disopyramide), drugs to treat mental disorders or symptoms of depression, including monoamine oxidase inhibitors (phenelzine and isocarboxazid), tricyclic antidepressants (amitriptyline and imipramine), phenothiazines or antipsychotics, antifungal medications (like ketoconazole and itraconazole), HIV medicines (e.g., atazanavir, ritonavir, indinavir, nelfinavir, saquinavir), antibiotics (furazolidone, clarithromycin, telithromycin), drugs to treat an underactive thyroid gland (such as levothyroxine), medicines for the treatment of Hodgkin's (procarbazine) and Parkinson's (levodopa) diseases, labor induction medications (such as oxytocin).

Do not take the medicine if you are pregnant or lactating without consulting a doctor.

Do not give Flutiform Transhaler to children under 12 years, unless directed by your child's doctor.

Q: What is Flutiform Transhaler indicated for?

A: The medication is indicated for the regular treatment of asthma and COPD, including chronic bronchitis and emphysema. The use of Flutiform Transhaler helps prevent symptoms like shortness of breath, wheezing, chest tightness, and cough, thus facilitating breathing difficulties.

Q: How much and for how long should I take the medication?

A: Flutiform Transhaler should be used on a regular basis for optimum results. The recommended dosage is 2 inhalations (puffs) in the morning and 2 inhalations (puffs) in the evening. Do not change the dosage or stop using the medicine, unless advised by your doctor.

Q: Is it safe to use the inhaler during pregnancy or while breastfeeding?

A: The administration of Flutiform Transhaler should only be considered if the expected benefits outweigh the risks. Do not take the medication without consulting your doctor.

Target Point Shipping Method Tracking Delivery Time Price
Worldwide Shipping

Worldwide Shipping

Registered Mail  Not trackable 14-21 business days USD 15.00 per order
EMS  Trackable, where available 5-9 business days USD 25.00 per order

Delivery time is:

Registered Mail - 14-21 business days, price - USD 15.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 25.00, signature is required on delivery.
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