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Orcibest® functions as a bronchodilator and is used to treat patients suffering from asthma or chronic bronchitis. It operates by relaxing the muscles in the lungs and airways allowing easier and more comfortable respiration. This makes the medication useful for treating and preventing wheezing, shortness of breath, coughing, chest tightness, and breathing difficulties. Orcibest® is also helpful in the treatment of bradycardia (slow heart rate). Orcibest® is meant for use in patients over 4 years of age.

Other names for this medication:
Aisopen, Alotec®, Alupent®, Asritin, Asthnil, Astmopent®, Brondin, Cosica, Kopidin, Likancough, Metaprel, Metaproterenol Sulfate Silarx, Nonasma, Olupent, Orcitran, Salupen, Sucroxine, Trancosu, Yupent

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Adco-Lincopent, Airtec FB®, Airlast, Adco-Combineb, Ambrodil®-S, Antran, Asmalex, Asmavent®-B, Bekform Rotacaps®, Beclate® Inhaler, Beclasma® HFA, Belar-G, Bevent Easecaps, Bisolvon® Linctus Da, Bricanyl®, Breva, Bronconemox, Broncodual® Compuesto, Bronko Plus Forte, Butocort, Butosol, Cloval® Compuesto, Combair®, Combivent®, Flohale Inhaler, Flupulmin, Ipramol®, Ipravent Inhaler, Ipravent-S, Mastifen-S, Mucovent®, Nebulasma®, Prednisolone, Seroflo Rotacaps®, Singulair®, Silomat Comp®, Theo Asthalin Forte, Quibron®-T/SR

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Orcibest® is used to relieve symptoms associated with chronic bronchitis, asthma, emphysema, and bradycardia. The medicine is manufactured by Zydus Cadila and contains Orciprenaline as an active substance. Orciprenaline is a moderately selective beta2-adrenergic agonist that works by opening the airways in the lungs, making breathing easier. The medicine also assists in reducing or preventing certain mediators of hypersensitivity from being released into the body, which may help reduce the occurrence of symptoms. The effect produced by Orcibest® tablets can usually be felt 30 minutes after taking a dose and lasts for 3 to 6 hours.


Orcibest® tablets are used for the treatment, control, prevention, and improvement of the following diseases, conditions and symptoms:

- asthma;


- emphysema;

- bradycardia.

MOA (mechanism of action):

Orciprenaline is a moderately selective beta2-adrenergic agonist that stimulates beta2-adrenergic receptors of the smooth muscle in the lungs, uterus, and vasculature and which has a minimal or no effect on beta1-adrenergic receptors. Orcibest® works by increasing the levels of cAMP (cyclic adenosine monophosphate, a messenger used for transferring the effects of certain hormones into cells). Increases in the levels of cAMP allow the bronchial smooth muscle to relax, thereby opening up the muscles in the airways. Asthma and other conditions in which the passage of air into the lungs is obstructed can, therefore, be alleviated, due to the opening of the airways which makes breathing easier. In the treatment of bradycardia, Orciprenaline increases the perception of beta-adrenergic receptors and improves atrioventricular conductivity, leading to increased excitation and increased heart rate.


The Orcibest® should be swallowed as a whole. Do not chew, crush or break the tablets. The medicine may be taken with or without food.

- Adults: 10 mg 3 or 4 times daily.

- Children (4 - 11 years): 5 mg 3 times daily.

- Children (12 years and older): 10 mg 3 times daily.

Missing a dose

If you miss a dose of Orcibest® you should take it as soon as you remember. If it is the time for the next dose you should continue your regular dosing schedule. Do not exceed the doctor’s recommended dose.


If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Orcibest® tablets are:

  • - headache
  • - tremor
  • - dizziness
  • - weakness
  • - cough
  • - nausea
  • - tachycardia
  • Less common side effects include:
  • - increased difficulty breathing
  • - rapid or increased heart rate
  • - irregular heartbeat
  • - chest pain or discomfort
  • - insomnia
  • - restlessness

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.


Do not take the tablets if you are allergic to Orciprenaline or any ingredients of this medication.

Do not use Orcibest® if you are taking beta-blockers.

Do not take the drug if you have an irregular heartbeat or heart disease.

Do not use Orcibest® if you have hypertrophic obstructive cardiomyopathy.

Do not take the medicine if you have diabetes.

Do not use the tablets in patients with hypothyroidism.

Do not combine Orcibest® tables with the use of ipratropium, propranolol, monoamine oxidase inhibitors, sympathomimetics and tricyclic antidepressants.

Do not give the drug to patients under 4 years of age.

Avoid drinking alcohol while taking Orcibest®.

Q: Can Orcibest® tablets be used for slow heart rate and constriction of the air passages?

A: Yes, slow heart rate and constriction of the air passages are among the most common reported uses for this drug. Please do not use Orcibest® for slow heart rate and constriction of the air passages without consulting first with your doctor.

Q: How does this medication work?

A: Orcibest® belongs to a class of medications known as bronchodilators. It is used to relieve symptoms associated with asthma, chronic bronchitis, emphysema, and other lung conditions. It works by opening the airways, making breathing easier. Orcibest® is also helpful in the treatment of bradycardia, as it improves atrioventricular conductivity that increases a heart rate. The effects of this medication can usually be felt within 30 minutes of taking a dose and lasts for 3 to 6 hours.

Q: How should I use Orcibest®?

A: Orcibest® should always be used according to your physician's directions to get the safest and most effective results from treatment. The doses are prescribed depending on patient’s age, weight, current health, the condition being treated, and the severity of symptoms. These medication should be swallowed with a glass of water and may be taken with or without food, although a snack or meal is suggested before use if you get an upset stomach. Do not crush, split, or chew the tablets before use to avoid destroying or altering the effects of their contents.

Q: Is Orcibest® safe during pregnancy or when breastfeeding?

A: It is not recommended to use during pregnancy or if breastfeeding unless necessary and the benefits outweigh the risks. Do not take the medicine without consulting your doctor.

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