Description
Fasigyn® manufacturer is Pfizer.
Fasigyn® tablets contain active ingredient is Tinidazole, a 5-nitroimidazole anti-parasitic agent, which belongs to a drug class Amebicides, Antimalarials and gynecological Antiinfectives.
Indications:
- genitourinary tract infections in both women and men caused by trichomonas vaginalis, including vaginitis, giardiasis, trichomoniasis, amebiasis, endometritis or abscess in the ovaries/fallopian tubes;
- prevention of anaerobic infections following gynecological or abdominal surgery;
- bacterial infections in the abdomen (peritonitis); abscess in the pelvic cavity;
- bacterial infection of the blood (septicaemia);
- bacterial skin and soft tissue infections;
- bacterial infections of the respiratory tract, such as pneumonia or lung abscesses;
- painful inflammation and ulcers of the gums (ulcerative gingivitis);
- parasitic gut infection caused by the protozoa Giardia lamblia (giardiasis);
- amoebic infection of the liver or intestine;
- part of a treatment to fight Helicobacter pylori (infection associated with stomach and duodenal ulcers).
MOA (mechanism of action):
Tinidazole is used to treat infections caused by bacteria and other microorganisms called protozoa. Tinidazole enters bacterial and protozoal cells and interferes with their DNA. It destroys the DNA and does not allow the bacteria and protozoa to form new genetic material. This ultimately results in death of microorganisms, which gets rid of the infection.
Dosage
Fasigyn® tablets should be taken with plenty of water with or after meal.
Swallow Fasigyn® tablets whole, do not chew or crush.
Fasigyn® is not recommended for use in children less than 12 years.
For urogenital Trichomoniasis: The recommended dose is 4 tablets (2 g) given as a single dose.
For amoebic involvement of the liver (a liver infection): the recommended dose is 3 to 4 tablets (1,5 to 2 g) once a day for 3 to 6 days.
For the infection associated with stomach ulcers: the recommended dose is 1 tablet (500 mg) taken twice a day.
For most bacterial infections: the recommended dose is 4 tablets (2 g) on the first day then 2 tablets (1 g) once a day or 1 tablet (500 mg) twice a day. The usual length of treatment is 5 to 6 days.
For bacterial vaginitis (a vaginal infection) and acute ulcerative gingivitis (a gum infection): the recommended dose is 4 tablets (2 g) given as a single dose. For vaginitis you may be given 4 tablets (2 g) on two consecutive days.
For protozoal infections (intestinal amoebiasis): the recommended dose is 4 tablets (2 g) once a day for 2 to 3 days.
Prevention of postoperative infections in adults (over 12 years): the recommended oral dose of 2 g approximately 12 hours before surgery.
Missing a dose
If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose of Fasigyn® to compensate the missed dose.
Overdose
If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.
Storage
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.