Description

Aquazide® is manufactured by Sun Pharmaceutical Industries. The active ingredient comprised in these tablets is Hydrochlorothiazide, an antihypertensive diuretic of thiazide class.

Indications:

- edema associated with congestive heart failure, hepatic cirrhosis, corticosteroid and estrogen therapy, and various forms of renal dysfunction (nephrotic syndrome, acute glomerulonephritis, and chronic renal failure);

- management of hypertension (alone or in combination with other antihypertensive drugs of a different class). Aquazide® usually does not effect normal blood pressure.

Aquazide® also can be used as an alternative oral agent for management of nephrogenic diabetes insipidus (do not confuse with diabetes mellitus or sugar diabetes), followed by abnormal production of urine (polyuria) and constant thirst (polydipsia).

MOA (mechanism of action):

Hydrochlorothiazide decreases elevated blood pressure by reducing the volume of blood. In particular, it acts on kidneys inhibiting the sodium and water reabsorption in the distal convoluted tubule (kidney nephron). By this action, it promotes the urine formation, so excessive fluid leaves the body as urine instead of getting into the bloodstream. Hydrochlorothiazide also thought to relax the muscles in the walls of blood vessels, thereby lowering peripheral vascular resistance.

Dosage

Aquazide® tablets should be swallowed whole and taken with a glass of water.

The exact dosage, as well as the course duration, must be determined by a doctor for each individual patient.

Aquazide® tablets are only for oral use.

Adults and elderly:

Foe edema: 25-100 mg a day as a single or divided intake. The tablets should be taken every other day or on 3 to 5 days each week.

For hypertension: 25-50 mg daily as a single or divided intake.

Children and infants:

For edema: 2 mg/kg daily as a single or divided intake. The highest recommended dose may be up to 3 mg/kg daily.

For hypertension: 1-2 mg/kg daily as a single or divided intake. The highest recommended dose may be up to 3 mg/kg daily.

Infants under 2 years of age should not be given more than 37,5 mg a day.

Children from 2 to 12 years of age should not be given more than 100 mg a day.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose.

Overdose

If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 20 and 25 degrees C and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with the use of Aquazide® are:

• upset stomach
• nausea and vomiting
• dizziness
• headache
• fever
• weakness
• skin rash
• allergic reactions (difficulty breathing, rash, itching, swelling on the face, lips, tongue)
• blurred vision
• eye pain
• dehydration

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Aquazide® if you are allergic to Hydrochlorothiazide or any other thiazide diuretic.

Do not take Aquazide® if you are allergic to any of the other ingredients comprised in Aquazide®.

Do not consume alcohol while using Aquazide® as it may decrease an antidiuretic effect of the medication.

Do not take Aquazide® if you have recently had sympathectomy.

Do not combine Aquazide® with the use of antidiuretics.

Do not take Aquazide® if you have anuria, hepatic coma or pre-coma, asthma, diabetes, gout, pancreatitis, hypercalcemia, hyperuricemia, hypochloremia, hypokalemia, hypomagnesemia, hyponatremia or systemic lupus erythematosus.

Do not take Aquazide® if you are currently taking nausea drugs (dolasetron), anti-inflammatory drugs for pain or swelling (aspirin, ibuprofen, naproxen, diclofenac), barbiturates for sleep or seizure control (secobarbital, pentobarbital, mephobarbital), heart medications (digoxin, dofetilide), antipsychotics (lithium, haloperidol), antidiabetics (chlorpropamide), amphetamines (lisdexamfetamine), high blood pressure medications (enalapril, perindopril, irbesartan), vitamin D or its analogs, muscle relaxants (diazepam, lorazepam, clonazepam), other diuretics or anticoagulants (warfarin).

It is recommended not to use Aquazide® in pregnant women unless considered absolutely necessary by your doctor.

It is strictly prohibited to breastfeed during the Aquazide® treatment course.

Q: What Aquazide® is used for?

A: Aquazide® is a diuretic and antihypertensive. It is used to treat edema associated with certain health conditions, like heart failure or renal dysfunction among others, and manage elevated blood pressure (hypertension).

Q: Is Aquazide® safe?

A: Aquazide® is safe as long as taken for prescribed condition and at prescribed doses.

Q: Can pregnant women use Aquazide®?

A: It is recommended not to use Aquazide® in pregnant women unless considered absolutely necessary by your doctor.

Target Point	Shipping Method	Tracking	Delivery Time	Price
Worldwide Shipping		Not trackable	21-30 business days	USD 15.00 per order
		Trackable, where available	14-21 business days	USD 25.00 per order

Delivery time is:

Registered Mail - 21-30 business days, price - USD 15.00, no signature is required on delivery.
EMS - 14-21 business days, price - USD 25.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

This is exactly how your parcel will look like (pictures of a real shipping item). It has a look of a regular private letter and does not disclose its contents. Size - 9.4x4.3x0.3 inches (24x11x0.7cm).