Description
Cenforce-D® is produced by Centurion. It is a combined medication that prevents men from ejaculating prematurely and helps to sustain an erection long enough for normal, satisfying sexual intercourse. Cenforce-D® contains two active ingredients – Sildenafil, a phosphodiesterase type 5 inhibitor, and Dapoxetine, short-acting serotonin reuptake inhibitor (SSRI).
Indications:
- erectile dysfunction or impotence;
- prematurity of ejaculation (PE).
Sildenafil is approved for the treatment of PAH (pulmonary arterial hypertension).
MOA (mechanism of action):
Sildenafil suppresses the enzyme phosphodiesterase type 5 (PDE-5). PDE-5 usually breaks down chemical messenger called cyclic GMP, which normally widens the blood vessels in the penis by relaxing muscles in the blood vessel walls. This delivers more blood to the penis, inducing a rigid erection. When the PDE-5 is inhibited, blood vessels are kept dilated longer, which improves blood flow to the penis and helps maintain an erection. Dapoxetine increases the activity of serotonin, a neurotransmitter that is involved in passing messages between nerve cells, including those that result in ejaculation. Enhanced activity of serotonin aids in increasing the time it takes to ejaculate and improves control over the ejaculation. Initially, Dapoxetine was created as an antidepressant.
Dosage
Swallow a pill whole with a drink of water.
Take one pill of Cenforce-D® orally 1 hour prior sexual activity.
Precautions:
Cenforce-D® pills are best taken with food.
Avoid consuming products containing grapefruit, as it may interfere with the medication's effectiveness.
Cenforce-D® does not protect you or your partner from sexually transmitted diseases (including HIV) or from pregnancy.
Take Cenforce-D® tablet not more than once every 24 hours.
It should only be taken when sexual activity is anticipated and is not intended as a regular treatment that is taken each day.
Missing a dose
Cenforce-D® is used only when needed, therefore missed dosages are not relevant. Do not exceed the doctor's recommended dose. Do not take a double dose.
Overdose
If you take an overdose of Cenforce-D®, you should seek emergency medical attention or contact your healthcare provider immediately.
Storage
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.