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Besivance ophthalmic solution's raw material is Besifloxacin – a fourth-generation antibiotic from the Fluoroquinolone family (also known as Quinolones). It is the only topical ophthalmic chlorofluoroquinolone.


- bacterial conjunctivitis caused by susceptible microorganisms.

MOA (mechanism of action):

Besifloxacin provides potent inhibition of bacterial DNA replication. It binds to bacterial DNA gyrase and topoisomerase IV enzymes. This suppresses enzymatic function and results in split DNA strands. Finally, DNA fragmentation and interfering with DNA replication ultimately cause bacterial cell death. Besifloxacin has been shown to be active against Aerococcus viridans, CDC coryneform group G, Corynebacterium pseudodiphtheriticum, Corynebacterium striatum, Haemophilus influenzae, Moraxella catarrhalis, Moraxella lacunata, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus hominis, Staphylococcus lugdunensis, Staphylococcus warneri, Streptococcus mitis group, Streptococcus oralis, Streptococcus pneumoniae, Streptococcus salivarius).


Instill into the treated eye(s) 3 times a day, 4 to 12 hours apart, for 7 days.

Use Besifloxacin eye drops at around the same times every day.


Besifloxacin solution is not for injection.

Besifloxacin solution is associated with allergic reactions, even following a single dose. Discontinue using drops immediately and contact your physician at the first sign of a rash or allergic reaction.

Prolonged use of Besivance ophthalmic solution may result in overgrowth of non-susceptible organisms, including fungi. If superinfection occurs, discontinue using these drops and institute alternative therapy.

Avoid contaminating the applicator tip with eye, fingers or another source.

Besivance ophthalmic solution contains the preservative benzalkonium chloride, which may cause eye irritation.

Besivance eye drops may cause your vision to blur temporarily after you have applied them into your eye. Do not drive or operate machinery until this has worn off.

Patients should not wear contact lenses while using Besifloxacin solution for eye infection.

Wash your hands before using the eye drops.

Missing a dose

If you miss a dose you should instill it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not instill a double dose to make up for a missed one.


If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately. A topical overdose of Besivance ophthalmic solution may be flushed from the eye(s) with lukewarm tap water.


Store at cool room temperature, away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use. Use within one month after opening a container. Keep out of the reach of children.

Side effects

The most common side effects associated with Besivance ophthalmic solution are:

  • red, itchy, or irritated eyes
  • eye pain
  • blurred vision
  • headache

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.


Besivance ophthalmic solution is not for use in children under 1 year of age.

Besivance ophthalmic solution is not for injection and hence the solution should not be injected subconjunctivally, nor should it be introduced directly into the anterior chamber of the eye.

Do not use Besivance ophthalmic solution if you are allergic to Besifloxacin or to other Fluoroquinolones.

Do not use Besivance ophthalmic solution if you are allergic to any ingredient comprised in Besivance ophthalmic solution.

Do not use Besivance ophthalmic solution if you have a history of severe allergic reactions associated with using antibiotics.

During therapy with Besivance ophthalmic solution, soft contact lenses should not be worn.

Consult your doctor before using Besivance ophthalmic solution if you are pregnant, plan to have a baby or are breastfeeding.

Q: What is Besivance ophthalmic solution used for?

A: Besivance ophthalmic solution is used as eye drops for the treatment of bacterial conjunctivitis (inflammation of the conjunctiva) in patients over 1 year of age. Besivance eye drops work locally on the eye surface so that the solution shouldn't be injected.

Q: Is Besivance ophthalmic solution safe?

A: Besivance ophthalmic solution is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Q: Can I use Besivance ophthalmic solution during pregnancy?

A: Besivance ophthalmic solution should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Target Point Shipping Method Tracking Delivery Time Price
Worldwide Shipping

Worldwide Shipping

Registered Mail  Not trackable 14-21 business days USD 15.00 per order
EMS  Trackable, where available 5-9 business days USD 25.00 per order

Delivery time is:

Registered Mail - 14-21 business days, price - USD 15.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 25.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

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