Description
Prilox® Cream is produced by Neon. The active ingredients are Lidocaine and Prilocaine, local anesthetics used to produce a temporary loss of sensation on the area where the drug is applied.
Indications:
- topical anesthesia to prevent pain associated with injections (inserting needle under skin), blood sampling (the drawing of blood from a vein), minor surgical procedures (e.g., removing genital warts), cleansing or removal of damaged skin of leg ulcers.
MOA (mechanism of action):
Lidocaine and Prilocaine are amide-type local anesthetics that produce analgesic effects. They both stabilize neuronal membranes and provide local anesthetic action by inhibiting the ionic fluxes required for the initiation and conduction of impulses that deliver pain signals to the brain.
Lidocaine has a beneficial effect on delaying ejaculation. That is why it can be used in a form of spray by individuals with PE (premature ejaculation), as it desensitizes the head of a penis allowing man prolong sexual activity.
Directions for use
One gram of cream pressed out of a tube is approximately 3,5 cm.
For skin before small procedures (such as having a needle put in or minor skin operations):
Adults and adolescents over 12 years: the usual dose is 2 g. Put the cream on at least 1 hour before the procedure (unless the cream is being used on the genitals). Do not put it on more than 5 hours before.
Infants 0-2 months: up to 1 g of cream on a skin area not larger than 10 cm2 in size, 1 hour before the procedure. One single dose for 24-hour period.
Infants 3-11 months: up to 2 g of cream on a total skin area not larger than 20 cm2, 1 hour (max. 4 hours) before the procedure. Two doses at 12-hours interval may be given in any 24 hour period.
Children 1-5 years: up to 10 g of cream on a total skin area not larger than 100 cm2, 1 hour (max. 5 hours) before the procedure.
Children 6-11 years: up to 20 g of cream on a total skin area not larger than 200 cm2, 1 hou (max. 5 hours) before the procedure.
For skin prior to removal of wart-like spots called “mollusca”:
The usual dose depends on the child’s age and is used for 30 to 60 minutes (30 minutes if the patient has atopic dermatitis). Check it with your doctor or pharmacist on how much cream to use.
For genital skin before injections of local anesthetics only for individuals over 12 years of age:
The usual dose is 1 g of cream (1-2 g for female genital skin) for each area of skin that is 10 cm2. The cream is put on under a dressing for 15 minutes on male genital skin and for 60 minutes on female genital skin.
For genitals before minor skin surgery (removing warts) only for individuals over 12 years of age:
The usual dose is 5- 10 g of cream for 10 minutes without dressing. The procedure should then start instantly.
For leg ulcers before cleaning or removal of damaged skin only in adults under doctor's supervision:
The usual dose is 1-2 g of cream for each area of skin that is 10 cm2 up to a total of 10 g. The cream is put on under an airtight dressing such as plastic wrap. This is done for 30-60 minutes before the ulcer is to be cleansed.
Precautions:
Do not use Prilox® Cream on areas with skin rash, cuts, grazes or other open wounds (with the exception of a leg ulcer), in or near the eyes, inside the nose, ear or mouth, in the back passage (anus), on the genitals of children.
Prilox® Cream should be used on the genitals and leg ulcers under doctor or nurse supervision.
For use in children under 2 years of age, consult your pharmacist.
If you are unsure how to measure the applied amounts, consult your pharmacist.
Avoid exposure to extreme hot or cold temperatures (e.g. food, drink) until complete sensation has returned.
Avoid contact Prilox® Cream with the eyes because numbness in the eyes may prevent you from noticing if you get something in your eye. If you unintentionally get Prilox® Cream in your eye, immediately rinse it well with lukewarm water or salt (sodium chloride) solution.
Missing a dose
Prilox® Cream is used only when needed, therefore missed dosages are not relevant. Do not exceed the doctor's recommended dose. Do not apply a double dose of Prilox® Cream.
Overdose
If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.
Storage
Store at room temperature up to 30 degrees C (86 degrees F) and away from excess moisture and heat. Do not freeze. Throw away any unused medicine after the expiration date. Keep out of the reach of children.