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About Advent® Drops

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Advent® Drops manufacturer is Cipla.

Advent® Drops comprise Amoxicillin and Clavulanic Acid as raw materials.

Amoxicillin is an Aminopenicillin antibiotic of broad-spectrum activity, which fights infection by inhibiting bacterial cell wall synthesis. Clavulanic Acid is a beta-lactamase inhibitor, used to enhance Amoxicillin’s efficacy.


- upper respiratory tract infections (including ENT) (e.g., recurrent tonsillitis, sinusitis, otitis media);

- lower respiratory tract infections (e.g., acute exacerbation of chronic bronchitis, lobar and bronchopneumonia);

- genito-urinary tract infections (e.g., cystitis, urethritis, pyelonephritis);

- skin and soft tissue infections (e.g., boils, abscesses, cellulitis, wound infections, animal bites);

- bone and joint infections (e.g. osteomyelitis);

- dental infections (e.g., dentoalveolar abscess, severe dental abscess with spreading cellulitis);

- other infections (e.g., intra-abdominal sepsis, septic abortion, puerperal sepsis).

Advent® Drops are also indicated for prophylaxis of infections which may be associated with major surgical procedures such as gastrointestinal, pelvic, head and neck, cardiac, renal, joint replacement and biliary tract.

Advent® Drops will not be effective for viral infections like common cold or flu, or for yeast infection.

MOA (mechanism of action):

Amoxicillin destroys bacterial cell wall by preventing the synthesis of a substance called peptidoglycan, vital for bacteria's survival. Clavulanic Acid in its turn deactivates a beta-lactamase enzyme produced by some bacteria to hinder the action of Amoxicillin.

Amoxicillin is effective against gram-positive bacteria, including Staphylococcus spp. (except strains producing penicillinase), Streptococcus spp; aerobic gram-negative bacteria: Neisseria Gonorrhoeae, Neisseria Meningitidis, Escherichia Coli, Shigella spp., Salmonella spp., Klebsiella spp.


Advent® Drops tablets are taken orally (by mouth).

Advent® Drops should be administered using supplied syringe doser.

According to a child's weight, the dose should be administered once every 8 hours.

Advent® Drops are for infants aged 3 to 24 months (based on body weight 1-10 kg).

1 kg = 0,13 ml; 1,5 kg = 0,20 ml; 2 kg = 0,27 ml; 2,5 kg = 0,33 ml;

3 kg = 0,40 ml; 3,5 kg = 0,47 ml; 4 kg = 0,53 ml; 4,5 kg = 0,60 ml;

5 kg = 0,67 ml; 5,5 kg = 0,73 ml; 6 kg = 0,80 ml; 6,5 kg = 0,87 ml;

7 kg = 0,93 ml; 7,5 kg = 1,00 ml; 8 kg = 1,07 ml; 8,5 kg = 1,14 ml;

9 kg = 1,20 ml; 9,5 kg = 1,27 ml; 10 kg = 1,34 ml.

These doses may be doubled in cases of severe infections.

Duration of the therapy shouldn't be extended beyond 14 days.


The dry powder should be reconstituted to form an oral suspension.

1. First, shake the bottle to loosen powder.

2. Twist and open the vial of sterile water given with the pack.

3. Slowly add sterile water into the bottle up to black arrow mark on the label.

4. Put the cap, and shake the bottle vigorously.

5. If necessary add more sterile water and shake again.

Shake well before each use.

Consume the reconstituted Advent® Drops within 7 days. Any extra portion left must be thrown away.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose of Advent® Drops to compensate the missed dose.


If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.


Store the reconstituted suspension in the refrigerator below 25 degrees C (77 degrees F). Throw away any unused reconstituted suspension after 7 days. Any extra portion left to be thrown away. Keep out of the reach of children.

Side effects

The most common side effects of Advent® Drops are:

  • antibiotic-associated diarrhoea
  • indigestion
  • nausea
  • vomiting
  • antibiotic-associated colitis

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.


Advent® Drops are for infants aged 3 to 24 months only (based on body weight between 4-10 kg).

Do not take Advent® Drops if you are allergic to Amoxicillin or any other antibiotic of the Penicillins.

Do not take Advent® Drops if you are allergic to Clavulanic Acid or any other ingredients comprised in Advent® Drops.

Do not take Advent® Drops if you have a history of severe allergic reactions associated with using antibiotics.

Do not take Advent® Drops if you are allergic to Nitroimidazole and its derivatives.

Do not take Advent® Drops if you have infectious mononucleosis, lymphatic leukemia, severe gastrointestinal infections, accompanied by diarrhea or vomiting, respiratory viral infection, allergic diathesis, bronchial asthma, hay fever.

Do not take Advent® Drops if you have a history of instructions for liver problems and jaundice, associated with the reception of Amoxicillin in combination with Clavulanic Acid.

Q: What are Advent® Drops used for?

A: Advent® Drops is a bactericidal beta-lactam antibiotic with a tangy orange flavor aimed to kill bacterial infections including urinary tract infections, respiratory tract infections, skin and soft tissue infections like wound infections and infected animal bites, dental infections in infants weighing between 4-10 kg.

Q: Can I treat cold or flu using Advent® Drops?

A: Advent® Drops treat only bacterial infections. It will not be effective for viral infections like common cold or flu, or for yeast infection.

Q: Are Advent® Drops safe for my child?

A: Advent® Drops are safe if used at prescribed doses for the prescribed treatment course as advised by the doctor.

Target Point Shipping Method Tracking Delivery Time Price
Worldwide Shipping

Worldwide Shipping

Registered Mail  Not trackable 14-21 business days USD 15.00 per order
EMS  Trackable, where available 5-9 business days USD 25.00 per order

Delivery time is:

Registered Mail - 14-21 business days, price - USD 15.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 25.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

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