Description
Melacare® Forte Cream is manufactured by Ajanta. The active substances comprised in Melacare® Forte Cream are Hydroquinone (benzene derivative of phenol type and a lightening agent), Tretinoin (retinol), and Mometasone Furoate (corticosteroid of glucocorticoid class).
Indications:
- hyperpigmentation (darkened areas of the skin, including freckles, chloasma (also known as melasma), age spots, liver spots and even acne scars).
Hyperpigmentation is a skin disorder associated with melanin overproduction, usually caused by genetic predisposition, sun exposure, pregnancy, hormone treatments, skin trauma, use of perfumes and deodorants, or hypothyroidism.
MOA (mechanism of action):
Hydroquinone blocks the enzyme tyrosinase – responsible for melanin production, therefore breaks down the melanin pigment granules in the melanocytes and allows brown patches reverse to a normal complexion.
Tretinoin binds to specific retinoic acid receptors and regulates cell differentiation and growth. It stimulates new epithelial cells production while exfoliating the old skin cells. Thus, Tretinoin speeds up the cells regeneration and lightening of the skin.
Mometasone Furoate acts as an anti-inflammatory agent blocking the release of inflammatory mediators, such as prostaglandins and leukotrienes. It also decreases the risk of contact dermatitis development that may appear due to the Hydroquinone and Tretinoin application.
Dosage
Melacare® Forte Cream is for external use only. Do not apply to your eyes, mouth, inside of the nose, private parts, and any other mucosal surface.
Melacare® Forte Cream should be applied 1-2 times daily, preferably in the morning and at bedtime.
Melacare® Forte Cream is usually applied from several weeks to 2-3 months depending on skin condition and tolerance. Use Melacare® Forte Cream as long as recommended by your doctor.
How to use Melacare® Forte Cream:
1. Wash your hands and make sure the affected areas are clean and dry.
2. Take a small amount of the cream and gently massage it over the affected area avoiding mucosal surfaces.
3. Wash your hands after the cream application.
Precautions:
Do not use Melacare® Forte Cream for longer than 6 months.
You should use sunscreen product (SPF 15 at least) during the Melacare® Forte Cream treatment course.
If you need to treat a large area of the skin with Melacare® Forte Cream, divide the application into a few sessions. Do not apply this cream to large areas at once.
If you have sensitive skin, it is recommended to test the sensitivity to Melacare® Forte Cream. Apply a small amount of the cream to the inner side of your arm and wait for 24 hours. If no hypersensitivity reactions occur (such as severe itching, burning, swelling, vesicle formation, and inflammation), you can start the regular Melacare® Forte Cream treatment course.
Do not apply Melacare® Forte Cream to the irritated, itchy, cracked or burnt skin (sunburns and windburns included).
Do not cover the Melacare® Forte Cream application site with occlusive bandages or other covering.
Do not use Melacare® Forte Cream in combination with harsh skin products, medicated soaps and shampoos, products with drying effect on the skin, peeling agents, products containing alcohol, spices or lime.
Do not get permanent wave solutions and waxing products on skin being treated with Melacare® Forte Cream.
Do not apply skin moisturizers or makeup to the skin being treated with Melacare® Forte Cream 1 hour before and after the gel application.
Patients should use sunscreens (min. SPF 15) and protective clothing while using Melacare® Forte Cream.
Missing a dose
If you miss a dose you should apply it as soon as you remember about your missing. If it is time for the next dose you should continue your regular dosing schedule. Do not apply a double dose.
Overdose
Do not exceed the doctor's recommended dose. If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.
Storage
Store at a room temperature from 20 to 25 degrees C (68 to 77 degrees F) away from moisture and heat. Throw away the tube after the expiration date. Keep away from children.